Assemble Health Effects Data

 

 

Endpoint Assessment

• Use available data to identify adverse effects, focusing on those of concern for exposed populations
• Consider strengths and uncertainties in data
  
  

MOA Assessment

• What are expected targets, based on chemical structure, available data, and related chemicals?
• What is known about MOA for related chemicals?

Vulnerable Populations

• Assessment
• Use available data to assist in the risk management
  decision

Background Exposure Assessment

• Use available data to assist in the risk management decision

 

Integration

• Consider available dose-response information on chemical of
  interest and related chemicals
• Place chemical in appropriate category based on hazard, dose-
  response, or dose-response and exposure information

Results Reporting