Beyond Science and Decisions: From Problem Formulation to Dose-Response Assessment
Workshop 6
May 28, 29, 30, 2013

Case Studies and Presentations

Tuesday, May 28

Welcome - Julie Fitzpatrick, U.S. Environmental Protection Agency

Introduction - Lynne Haber, Toxicology Excellence for Risk Assessment

• Presentation

Case Study: Endogenous Formation Implications for Formaldehyde Carcinogenicity
Robinan Gentry, Environ International Corporation; Tom Starr, TBS Associates; Jim Swenberg, University of North Carolina Chapel Hill; Jeffry Schroeter, Applied Research Associates

• Abstract
• Summary
• Case Study
• Presentations
  • Robinan Gentry -- Endogenous Formation: Implications for Formaldehyde Carcinogenicity
  • Jim Swenberg -- Endogenous Chemical Risk Assessment: Formaldehyde as a Case Example
  • Tom Starr – A Novel Bottom Up Approach to Bounding Potential Human Cancer Risks from Endogenous Chemicals
  • Jeff Schroeter – Using CFD modeling and dosimetry as a framework to incorporate biological data into a chemical assessment
  • Robinan Gentry – Putting it all together

Wednesday, May 29

Keynote - Ken Olden, U.S. EPA, National Center for Environmental Assessment

Pathway-Based Regulatory Toxicology and Alternatives to Animal Testing
Thomas Hartung, Johns Hopkins Bloomberg School of Public Health

• Presentation
  
  

Recent International Developments in Mode of Action/Adverse Outcome Pathway Analysis
Bette Meek, University of Ottawa

• Presentation

Health and Environmental Sciences Institute (HESI) RISK21 Program
Tim Pastoor, Syngenta Crop Protection, Inc.

• Presentation

The HESI RISK21 Quantitative Key Events Dose Response Framework (Q-KEDRF)
Ted Simon, Ted Simon, LLC

• Presentation

Case Study: Naphthalene Carcinogenicity: Hypothesis-Based Weight-of-Evidence Evaluation
Lorenz Rhomberg, Gradient; Lisa Bailey, Gradient

• Abstract
• Summary
• Case Study
• Publication
• Presentation
  
  

Case Study: Interpretation of 24-hour Sampling Data
Texas Commission on Environmental Quality (TCEQ): Roberta Grant; Joseph “Kip” Haney; Allison Jenkins
Ontario Ministry of Environment (MOE): Denis Jugloff; Julie Schroeder

• Abstract

TCEQ Approach

• Summary
• Case Study
• Presentation

MOE Approach

• Summary
• Case Study
• Presentation

 

 

 

For more information, please contact Lynne Haber.