Beyond Science and Decisions: From Problem Formulation to Dose-Response Assessment
Workshop 6
May 28, 29, 30, 2013

Case Studies and Presentations

Tuesday, May 28

Welcome - Julie Fitzpatrick, U.S. Environmental Protection Agency

Introduction - Lynne Haber, Toxicology Excellence for Risk Assessment

Case Study: Endogenous Formation Implications for Formaldehyde Carcinogenicity
Robinan Gentry, Environ International Corporation; Tom Starr, TBS Associates; Jim Swenberg, University of North Carolina Chapel Hill; Jeffry Schroeter, Applied Research Associates

Wednesday, May 29

Keynote - Ken Olden, U.S. EPA, National Center for Environmental Assessment

Pathway-Based Regulatory Toxicology and Alternatives to Animal Testing
Thomas Hartung, Johns Hopkins Bloomberg School of Public Health

Recent International Developments in Mode of Action/Adverse Outcome Pathway Analysis
Bette Meek, University of Ottawa

Health and Environmental Sciences Institute (HESI) RISK21 Program
Tim Pastoor, Syngenta Crop Protection, Inc.

The HESI RISK21 Quantitative Key Events Dose Response Framework (Q-KEDRF)
Ted Simon, Ted Simon, LLC

Case Study: Naphthalene Carcinogenicity: Hypothesis-Based Weight-of-Evidence Evaluation

Lorenz Rhomberg, Gradient; Lisa Bailey, Gradient

Case Study: Interpretation of 24-hour Sampling Data
Texas Commission on Environmental Quality (TCEQ): Roberta Grant; Joseph “Kip” Haney; Allison Jenkins
Ontario Ministry of Environment (MOE): Denis Jugloff; Julie Schroeder

TCEQ Approach

MOE Approach




For more information, please contact Lynne Haber.