HSN: 611

NAME: MINERAL-BASED CRANKCASE OIL

CAS-RN: 8002-05-9

DATE: 20180416

Risk Values - Summary Table

Summary Risk Table for:MINERAL-BASED CRANKCASE OIL
Risk Value Parameter OrganizationATSDRHealth CanadaIARCIPCSIPRVITER PRNSF IntlRIVMTCEQU.S.EPA
Oral: Non-Cancer
green check
--
--
--
--
--
--
--
--
--
Oral: Cancer
green check
--
green check
--
--
--
--
--
--
--
Inhalation: Non-Cancer
green check
--
--
--
--
--
--
--
--
--
Inhalation: Cancer
green check
--
green check
--
--
--
--
--
--
--
green check = Chemical evaluated and ITER data online.


Noncancer Oral Risk Values Table:

ITER Noncancer Oral Risk Table for: MINERAL-BASED CRANKCASE OIL
Risk Value Parameter OrganizationATSDRHealth CanadaIARCIPCSIPRVITER PRNSF IntlRIVMTCEQU.S.EPA
Risk Value Namechronic MRL
--
--
--
--
--
--
--
--
--
Risk Value*NA
--
--
--
--
--
--
--
--
--
Year1997
--
--
--
--
--
--
--
--
--
Base(Experimental)*NA
--
--
--
--
--
--
--
--
--
Basis(Adjusted)*NA
--
--
--
--
--
--
--
--
--
Uncertainty FactorNA
--
--
--
--
--
--
--
--
--
Critical Organ or EffectNA
--
--
--
--
--
--
--
--
--
SpeciesNA
--
--
--
--
--
--
--
--
--
StudyNA
--
--
--
--
--
--
--
--
--
Biomonitoring Blood
--
--
--
--
--
--
--
--
--
--
Biomonitoring Urine
--
--
--
--
--
--
--
--
--
--
View Specific:Click here
--
--
--
--
--
--
--
--
--
*In mg/kg body weight per day, unless otherwise specified.


Noncancer Oral Synopsis:

ATSDR has evaluated the noncancer oral toxicity data for used mineral-based crankcase oil. However, no meaningful minimal risk levels (MRLs) could be derived because of the substantial amount of uncertainty in the available NOAELs and LOAELs due to the variability in the composition of used mineral-based crankcase oil.

Noncancer Oral Specifics:

ATSDR

PEER:
The ATSDR Toxicological Profile has undergone internal agency reviews and has been externally reviewed by a peer review panel.

MOREI:
ATSDR (Agency for Toxic Substances and Disease Registry). 1997. Toxicological Profile for Used Mineral-based Crankcase Oil. U.S. Department of Health and Human Services, Public Health Service. September. Available at http://www.atsdr.cdc.gov/toxprofiles/tp102.html .

For the list of ATSDR minimal risk levels (MRLs), see http://www.atsdr.cdc.gov/mrls/index.html.


Cancer Oral Risk Values Table:

ITER Cancer Oral Risk Table for: MINERAL-BASED CRANKCASE OIL
Risk Value Parameter OrganizationATSDRHealth CanadaIARCIPCSIPRVITER PRNSF IntlRIVMTCEQU.S.EPA
Risk Value NameNA
--
NA
--
--
--
--
--
--
--
Risk Value*NA
--
NA
--
--
--
--
--
--
--
Year1997
--
1989
--
--
--
--
--
--
--
ClassificationNA
--
3
--
--
--
--
--
--
--
Target OrganNA
--
NA
--
--
--
--
--
--
--
SpeciesNA
--
NA
--
--
--
--
--
--
--
StudyNA
--
NA
--
--
--
--
--
--
--
Biomonitoring Blood
--
--
--
--
--
--
--
--
--
--
Biomonitoring Urine
--
--
--
--
--
--
--
--
--
--
View Specific:Click here
--
Click here
--
--
--
--
--
--
--
*In mg/kg body weight per day, unless otherwise specified.


Cancer Oral Synopsis:

ATSDR and IARC evaluated the oral carcinogenicity data for mineral-based crankcase oil (crude oil). IARC classifies crude oil as not classifiable as to its carcinogenicity to humans (Group 3), based on inadequate evidence for carcinogenicity in humans and limited evidence for carcinogenicity in experimental animals. The IARC evaluation considers the evidence of carcinogenicity in humans and experimental animals, as well as other data relevant to the evaluation of carcinogenicity and its mechanisms. IARC does not generally develop risk values or other estimates of potency. ATSDR has published a Toxicological Profile for Used Mineral-based Crankcase Oil. Although ATSDR discusses the carcinogenicity data in its Toxicological Profiles, it does not currently assess cancer potency or perform cancer risk assessments.

Cancer Oral Specifics:

ATSDR

PEER:
The ATSDR Toxicological Profile has undergone internal agency reviews and has been externally reviewed by a peer review panel.

MOREI:
ATSDR (Agency for Toxic Substances and Disease Registry). 1997. Toxicological Profile for Used Mineral-based Crankcase Oil. U.S. Department of Health and Human Services, Public Health Service. September. Available at http://www.atsdr.cdc.gov/toxprofiles/tp102.html .

For the list of ATSDR minimal risk levels (MRLs), see http://www.atsdr.cdc.gov/mrls/index.html.

Cancer Oral Specifics:

IARC

PEER:
Each IARC evaluation is developed by an international working group of experts, which meets to discuss and finalize the monograph text and to formulate the evaluations. Working Group members are chosen on the basis of their knowledge and experience, with due regard given to avoid situations where financial or other interests might affect the outcome of their work. The members of a Working Group are invited to serve in their individual capacities as scientists, and not as representatives of their governments or of any organization with which they are affiliated. Representatives of national and international agencies are also invited to the meetings, and others may attend as observers.

MOREI:
International Agency for Research on Cancer (IARC) Monographs. Occupational Exposures in Petroleum Refining; Crude Oil and Major Petroleum Fuels. 1989. Volume 45, page 8. Summaries &; Evaluations available at http://monographs.iarc.fr/ENG/Monographs/vol45/volume45.pdf

Additional information about the IARC Monographs (including ordering information and links to other Monographs) can be found at http://monographs.iarc.fr/


Noncancer Inhalation Risk Values Table:

ITER Noncancer Inhalation Risk Table for: MINERAL-BASED CRANKCASE OIL
Risk Value Parameter OrganizationATSDRHealth CanadaIARCIPCSIPRVITER PRNSF IntlRIVMTCEQU.S.EPA
Risk Value Namechronic MRL
--
--
--
--
--
--
--
--
--
Risk Value*NA
--
--
--
--
--
--
--
--
--
Year1997
--
--
--
--
--
--
--
--
--
Base(Experimental)*NA
--
--
--
--
--
--
--
--
--
Basis(Adjusted)*NA
--
--
--
--
--
--
--
--
--
Uncertainty FactorNA
--
--
--
--
--
--
--
--
--
Critical Organ or EffectNA
--
--
--
--
--
--
--
--
--
SpeciesNA
--
--
--
--
--
--
--
--
--
StudyNA
--
--
--
--
--
--
--
--
--
Biomonitoring Blood
--
--
--
--
--
--
--
--
--
--
Biomonitoring Urine
--
--
--
--
--
--
--
--
--
--
View Specific:Click here
--
--
--
--
--
--
--
--
--
*In mg/kg body weight per day, unless otherwise specified.


Noncancer Inhalation Synopsis:

ATSDR has evaluated the noncancer inhalation toxicity data for used mineral-based crankcase oil. However, no meaningful minimal risk levels (MRLs) could be derived because of the substantial amount of uncertainty in the available NOAELs and LOAELs due to the variability in the composition of used mineral-based crankcase oil.

Noncancer Inhalation Specifics:

ATSDR

PEER:
The ATSDR Toxicological Profile has undergone internal agency reviews and has been externally reviewed by a peer review panel.

MOREI:
ATSDR (Agency for Toxic Substances and Disease Registry). 1997. Toxicological Profile for Used Mineral-based Crankcase Oil. U.S. Department of Health and Human Services, Public Health Service. September. Available at http://www.atsdr.cdc.gov/toxprofiles/tp102.html .

For the list of ATSDR minimal risk levels (MRLs), see http://www.atsdr.cdc.gov/mrls/index.html.


Cancer Inhalation Risk Values Table:

ITER Cancer Inhalation Risk Table for: MINERAL-BASED CRANKCASE OIL
Risk Value Parameter OrganizationATSDRHealth CanadaIARCIPCSIPRVITER PRNSF IntlRIVMTCEQU.S.EPA
Risk Value NameNA
--
NA
--
--
--
--
--
--
--
Risk Value*NA
--
NA
--
--
--
--
--
--
--
Year1997
--
1989
--
--
--
--
--
--
--
ClassificationNA
--
3
--
--
--
--
--
--
--
Target OrganNA
--
NA
--
--
--
--
--
--
--
SpeciesNA
--
NA
--
--
--
--
--
--
--
StudyNA
--
NA
--
--
--
--
--
--
--
Biomonitoring Blood
--
--
--
--
--
--
--
--
--
--
Biomonitoring Urine
--
--
--
--
--
--
--
--
--
--
View Specific:Click here
--
Click here
--
--
--
--
--
--
--
*In mg/kg body weight per day, unless otherwise specified.


Cancer Inhalation Synopsis:

ATSDR and IARC evaluated the inhalation carcinogenicity data for mineral-based crankcase oil (crude oil). IARC classifies crude oil as not classifiable as to its carcinogenicity to humans (Group 3), based on inadequate evidence for carcinogenicity in humans and limited evidence for carcinogenicity in experimental animals. The IARC evaluation considers the evidence of carcinogenicity in humans and experimental animals, as well as other data relevant to the evaluation of carcinogenicity and its mechanisms. IARC does not generally develop risk values or other estimates of potency. ATSDR has published a Toxicological Profile for Used Mineral-based Crankcase Oil. Although ATSDR discusses the carcinogenicity data in its Toxicological Profiles, it does not currently assess cancer potency or perform cancer risk assessments.

Cancer Inhalation Specifics:

ATSDR

PEER:
The ATSDR Toxicological Profile has undergone internal agency reviews and has been externally reviewed by a peer review panel.

MOREI:
ATSDR (Agency for Toxic Substances and Disease Registry). 1997. Toxicological Profile for Used Mineral-based Crankcase Oil. U.S. Department of Health and Human Services, Public Health Service. September. Available at http://www.atsdr.cdc.gov/toxprofiles/tp102.html .

For the list of ATSDR minimal risk levels (MRLs), see http://www.atsdr.cdc.gov/mrls/index.html.

Cancer Inhalation Specifics:

IARC

PEER:
Each IARC evaluation is developed by an international working group of experts, which meets to discuss and finalize the monograph text and to formulate the evaluations. Working Group members are chosen on the basis of their knowledge and experience, with due regard given to avoid situations where financial or other interests might affect the outcome of their work. The members of a Working Group are invited to serve in their individual capacities as scientists, and not as representatives of their governments or of any organization with which they are affiliated. Representatives of national and international agencies are also invited to the meetings, and others may attend as observers.

MOREI:
International Agency for Research on Cancer (IARC) Monographs. Occupational Exposures in Petroleum Refining; Crude Oil and Major Petroleum Fuels. 1989. Volume 45, page 8. Summaries &; Evaluations available at http://monographs.iarc.fr/ENG/Monographs/vol45/volume45.pdf

Additional information about the IARC Monographs (including ordering information and links to other Monographs) can be found at http://monographs.iarc.fr/

NO Revision History: