Is that Benefit Worth its Risk?

As we all know, life can be complicated. Tools that are very useful for gardening, like a rake, can hurt pretty badly if stepped on the wrong way. This useful/hurtful idea extends to nearly all aspects of our lives. We can all think of numerous examples of this idea, like cars, electricity, or lawn mowers. This idea of useful/hurtful or benefit/risk also extends to chemicals, the most common ones to which we willingly expose ourselves are foods of various sorts. And while most of us can eat many foods in moderation without too many problems, we likely all know of folks with food allergies, some of which can be life threatening.

So how does one look at the useful/hurtful or benefit/risk for chemicals? In some cases, it’s easy. Everyone needs to drink dihydrogen monoxide (yep that’s water), or at least drink other fluids that contain a lot of water, like coffee, milk or beer. But we all know that one can drink too much water leading to a disturbance in nerve function; or too much coffee leading to irritability and heart palpitations; or to much milk leading some to have digestive problems; or too much beer leading to intoxication. In such cases many of us will naturally limit our consumption to gain the benefit of the chemical, but avoid the risk. In fact, this risk/benefit comparison is a common approach with exposure to many chemicals in our lives, or with other non-chemical aspects, such as that pesky garden rake.

We are exposed to tens of thousands of chemicals every day. You cannot escape this exposure! Coffee has over 1000 chemicals, the principle one being water. Our various foods contain just as many chemicals, and perhaps even more. Our houses and farms also contain numerous chemicals, and many, if not all, have huge benefits. For example, I grew sweet corn this year in a different patch of my garden. I hand weeded this corn 3 times. Despite this effort the weeds grew to be taller than my corn and my ears were correspondingly smaller than last year. My cousin grew sweet corn as well but sprayed Round-up where the corn had been planted before the corn emerged. Voila, fewer weeds; bigger ears of corn (and of course, bragging rights to my cousin). Even organic farming, which eliminates or greatly reduces the use of chemicals, has drawbacks such as increased in use of machinery, labor, fuel and emissions. Organic farming typically produces less food, at higher price, and which has been shown to not be any more nutritious than non-organic food. 

So how do we make this benefit/risk comparison with chemicals other that those found in drinks and food. The easiest way is to read the label of the chemical of concern, and importantly, follow directions (I know, guys, this can be hard to do.) A little bit of Round-up is good, so more is better, correct? Wrong. Follow the directions on the label. Industry and government scientists who study the risks of such chemicals have worked very hard to get the safety right and make the directions on the labels adhere to this safety work. We can all thank them by following the directions on the label.

Well what about all those chemicals we hear about in the news; they do not all have labels, correct? Correct, not all chemicals in the news, like ethylene oxide (a medical sterilent about which I have written before) or the “forever” chemicals (the most talked about one is perfluorooctanoate (PFOA) have labels. However, government scientists also work hard to set safe levels for these chemicals, and afterwards rules for how much can be found in our products. Although more uncertainty exists in this process, since the underlying data are often not as extensive as with chemicals that have labels. If you have questions about chemicals in the news, feel free to send them to me. I would be happy to try and answer them.

In the meantime, let’s all enjoy the many benefits that chemicals bring us, follow the labels when they are available to avoid their risks, and ask questions of appropriate experts when you are uncertain about how to proceed.

WEEL OEL

Occupational Exposure Limits (OELs) are designed to safeguard the health of healthy workers during their careers. These limits are based on the assumption of repeated daily exposure throughout a working lifetime, typically averaged over an 8-hour workday. Their purpose is to prevent both immediate (acute) and long-term (chronic) health issues arising from workplace exposures. It’s important to note that OELs are not intended for the general public, which includes vulnerable groups like infants, the elderly, and those with pre-existing health conditions.

Workplace Environmental Exposure Levels (WEELs) are health-based guidelines for chemical hazards in the workplace. These values represent air concentrations believed to protect the majority of workers from negative health effects resulting from occupational chemical exposure.

The WEEL Process
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The development of new or revision of existing WEELs is typically assigned to voluntarily designated subcommittees. A subcommittee usually comprises 3 – 4 members from the WEEL Committee. New WEELs are developed using the OARS-WEEL administrative standard operating procedure (SOP), while existing WEELs are usually revised every 10 years, unless the availability of significant new data which may impact the existing WEEL value compels the committee to make a revision sooner. The OARS-WEEL SOP contains procedures and guidelines governing conflicts of interest, draft document preparation, literature searches, draft document review, balloting process, post-ballot WEEL documentation quality assurance scientific review, and publication.

Once a subcommittee has prepared a draft WEEL document, a review of the draft is scheduled for the next available Committee meeting. The WEEL Committee members are expected to have reviewed all such drafts prior to the meeting. If no major changes are necessary to a draft, the attending Committee membership may, by a simple majority, approve the WEEL for balloting. Alternatively, the Committee may direct the subcommittee to revise the WEEL and present it for further discussion at a future meeting. If a ballot is not approved by a two-thirds majority of non-abstaining Committee members, it is discussed at the next Committee meeting to determine the appropriate course of action. Once the WEEL is approved by a two-thirds majority of non-abstaining Committee members, copies of ballot comments are forwarded to the designated subcommittee and all substantive comments must be addressed in the final draft. If resolution of a substantive comment results in a change to the WEEL value or a change in the basis for the value, the draft must be re-balloted.

Once all comments have been addressed on a successfully balloted draft, document formatting and editorial review are performed by TERA, before the draft WEEL document is made available for public comment (usually for a period of 30 days but may be extended if the need arises). After the public comment period has elapsed, comments are addressed by the subcommittee responsible for that specific draft, after which the WEEL documentation is submitted to Toxicology and Industrial Health (TIH), a peer-reviewed medical journal that covers research in the fields of occupational health and toxicology, for publication. A thorough review of the galley proof by the scientific content quality coordinator at TERA, and proofreaders and editors at TIH is the penultimate step before eventual publication of the WEEL documentation.

The WEEL Committee

The OARS-WEEL Committee is composed of volunteer experts specializing in the scientific determination of occupational exposure levels. This committee actively seeks a balanced representation of professionals from toxicology and industrial hygiene, drawing upon a diverse range of experience from industry, government, academia, and consulting. Importantly, each member contributes to the Committee based on their individual expertise and not as an official representative of their respective employer, organization, or agency.