Linkedin Facebook X-twitter Youtube Pinterest Envelope Viber

Risk Assessment Continuing Education (RACE)

Dose – Response Assessment Boot Camp

This course is a 5-day  intensive hands-on training in hazard characterization and dose-response assessment.  Beginners through expert toxicological risk assessors will learn advanced methods, as well as enhance their understanding and skills in the basics.  Course lectures are supplemented with daily hands-on application exercises.  For information on the dates of the next Boot Camp Course, registration and more details please see the Boot Camp webpage. Click here for the course brochure.

Occupational Risk Assessment Course

The 4-day Occupational Exposure Limits Course provides attendees wuith the knowledge to understand and apply methods for occupational risk assessment. The course will be aimed at core concepts in deriving and using occupational exposure limits. The course consists of interactive presentations and hands-on exercises.  For information on the dates of the next ORAC Course, registration and more details. Please click the link to email Dr. Bernard Gadagbui or contact him at 513.542.7475 Ext 104

Customized Courses

TERA also offers private Boot Camp training sessions for your staff (available as a 3, 4, or 5 –day course), and can provide risk assessment training at your site.  We will work with you to develop training materials tailored to your specific needs, using existing courses and/or developing new ones.  We can also meet with your group to discuss risk assessment issues on a less formal basis.  For more information on TERA’s training services, Please click the link to email Dr Michael Dourson or contact her at 513.542.7475 Ext 105

Web Continuing Education Courses

Web Continuing Education Courses

Practioners Guide to Risk Assessment for Developmental & Reproductive Toxicology (DART)

This 4 hour webinar is intended for health scientists and product stewardship professionals who need to consider the potential for reproductive and developmental effects of their chemicals or products. The learning objectives for this course are: interpreting adversity of DART endpoints; applying dose-response techniques; evaluating mode of action and human relevance; optimizing testing needs and strategies; and understanding key concepts in current risk assessment guidance for DART.

Dosimetric Adjustments in Dose Response Assessment (4 hours)

This 4 hour course is designed to provide basic training in dosimetric adjustments involved in dose-response assessment.  The participants will learn the significance of conducting dosimetric adjustment, and how to conduct it.  The topics will include interspecies oral dose adjustment for noncancer and cancer assessment, cancer unit risk or slope factor conversion, inhalation exposure concentration unit conversion, human equivalent concentration (HEC) calculation for particle and vapor exposure.

 

Bench Mark Dose Modeling (8 hours)

This 8 hour course is designed to give an overview of benchmark modeling software for cancer and noncancer dose-response assessment, and provide hands-on experience in using the EPA BMDS software.  Through this training course, participants will learn the basic concept of the BMD approach, appropriate application of BMD modeling in cancer and noncancer dose-response assessment, model and parameter selections during BMD modeling, data selection and model run, and selecting an appropriate BMD as a point of departure in a human health risk assessment.  This training will cover all the BMD models available in the latest version of EPA’s BMDS software, such as continuous models, dichotomous models, cancer model, and nested models. 

Noncancer & Cancer Risk Assessment (6 hours)

This 6 hour course provides an overview and basic concepts of noncancer and cancer risk assessment followed by detailed discussion of the methods used in chemical risk assessment. The presentation also covers the application of the latest methodology used risk assessment. A step-by-step discussion of sample cases will be conducted to further elaborate the decision making process in chemical risk assessment.

Use of Chemical Specific Adjustment Factor (CSAF) (6 hours)

This 6 hour course will teach the participants methods for application of the new IPCS guidance on the use of chemical-specific adjustment factors (CSAFs), as a refinement to the uncertainty factor approach.  A review of the use of uncertainty factors and historical perspective on the reliance on quantitative data to develop values for inter- and intra-species extrapolation will be presented as background.  The course will focus on the IPCS methodology for CSAF development, including the thinking process and steps used for evaluating data.  Examples and classroom activities will be used as instructional aids.

For more information contact Bernard Gadagbui at gadagbui@tera.org

Corporate Info

Resources

Our Brands

  • ITER ITER

Contacts

  • 1250 Ohio Pike, Suite 197, Cincinnati Ohio 45102
  • 513.488.1990
  • TERA@TERA.ORG

You will be redirected to a secure payment portal

Linkedin Facebook X-twitter Youtube Pinterest

WEEL OEL

Occupational Exposure Limits (OELs) are designed to safeguard the health of healthy workers during their careers. These limits are based on the assumption of repeated daily exposure throughout a working lifetime, typically averaged over an 8-hour workday. Their purpose is to prevent both immediate (acute) and long-term (chronic) health issues arising from workplace exposures. It’s important to note that OELs are not intended for the general public, which includes vulnerable groups like infants, the elderly, and those with pre-existing health conditions.

Workplace Environmental Exposure Levels (WEELs) are health-based guidelines for chemical hazards in the workplace. These values represent air concentrations believed to protect the majority of workers from negative health effects resulting from occupational chemical exposure.

The WEEL Process
Click Here

The development of new or revision of existing WEELs is typically assigned to voluntarily designated subcommittees. A subcommittee usually comprises 3 – 4 members from the WEEL Committee. New WEELs are developed using the OARS-WEEL administrative standard operating procedure (SOP), while existing WEELs are usually revised every 10 years, unless the availability of significant new data which may impact the existing WEEL value compels the committee to make a revision sooner. The OARS-WEEL SOP contains procedures and guidelines governing conflicts of interest, draft document preparation, literature searches, draft document review, balloting process, post-ballot WEEL documentation quality assurance scientific review, and publication.

Once a subcommittee has prepared a draft WEEL document, a review of the draft is scheduled for the next available Committee meeting. The WEEL Committee members are expected to have reviewed all such drafts prior to the meeting. If no major changes are necessary to a draft, the attending Committee membership may, by a simple majority, approve the WEEL for balloting. Alternatively, the Committee may direct the subcommittee to revise the WEEL and present it for further discussion at a future meeting. If a ballot is not approved by a two-thirds majority of non-abstaining Committee members, it is discussed at the next Committee meeting to determine the appropriate course of action. Once the WEEL is approved by a two-thirds majority of non-abstaining Committee members, copies of ballot comments are forwarded to the designated subcommittee and all substantive comments must be addressed in the final draft. If resolution of a substantive comment results in a change to the WEEL value or a change in the basis for the value, the draft must be re-balloted.

Once all comments have been addressed on a successfully balloted draft, document formatting and editorial review are performed by TERA, before the draft WEEL document is made available for public comment (usually for a period of 30 days but may be extended if the need arises). After the public comment period has elapsed, comments are addressed by the subcommittee responsible for that specific draft, after which the WEEL documentation is submitted to Toxicology and Industrial Health (TIH), a peer-reviewed medical journal that covers research in the fields of occupational health and toxicology, for publication. A thorough review of the galley proof by the scientific content quality coordinator at TERA, and proofreaders and editors at TIH is the penultimate step before eventual publication of the WEEL documentation.

The WEEL Committee

The OARS-WEEL Committee is composed of volunteer experts specializing in the scientific determination of occupational exposure levels. This committee actively seeks a balanced representation of professionals from toxicology and industrial hygiene, drawing upon a diverse range of experience from industry, government, academia, and consulting. Importantly, each member contributes to the Committee based on their individual expertise and not as an official representative of their respective employer, organization, or agency.